Lapis ISSN 2398-2969

Hematology: monocyte

Synonym(s): Mononuclear phagocytes

Contributor(s): Michael Waters, Molly Varga, Vetstream Ltd

Overview

  • Monocytes are usually the largest cells present on the blood film. The nucleus may vary from round to lobed. There is a moderate amount of cytoplasm, which may be vacuolated.
  • Monocytes circulate in the blood briefly   →   enter the tissues   →   transform into macrophages   →   do not re-enter the circulation. The ratio of circulating monocytes to macrophages is ~1:400.
  • The mononuclear phagocyte system (bone marrow precursors, monocytes and macrophages) phagocytoses and destroys microorganisms, phagocytoses particulate material (foreign bodies, tissue and cellular debris), interacts with lymphocytes in immune reactions, produces interferon and regulates hematopoiesis.

Sampling

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Tests

Methodologies

  • Differential white blood cell count.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMed.

Other sources of information

  • Campbell T W & Ellis C K (2007)Avian and Exotic Hematology and Cytology.3rd edn. Wiley-Blackwell. ISBN: 978-0813818115.
  • Fudge A M (1999)Laboratory Medicine. Avian and Exotic Pets.W B Saunders Co. ISBN: 0721 676 790.


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