Lapis ISSN 2398-2969

Blood biochemistry: urea

Synonym(s): Blood urea nitrogen, BUN

Contributor(s): Anna Meredith, Vetstream Ltd, Michael Waters, John Chitty

Overview

  • Produced in liver from ammonia derived from tissue/dietary protein and excreted by kidneys.
  • Important marker of kidney function, protein metabolism and upper gastrointestinal tract hemorrhage.

Sampling

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Tests

Methodologies

  • Typically measured as (total) blood urea nitrogen (BUN).
  • Blood strips can be used to get a rapid results; they do not give precise readings but will show if levels are significantly elevated.

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Only significant in conjunction with other laboratory and clinical findings.

Most useful to assess in conjunction with a urine specific gravity.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Harcourt-Brown F (2013) Diagnosis of renal disease in rabbits. Vet Clin North Am Exotic Anim Pract 16 (1),145-174
  • Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.

Other sources of information

  • Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, London, UK.
  • Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. pp 124-137. BSAVA, Gloucester, UK.
  • Saunders R A & Rees Davies R (2005) Notes on Rabbit Internal Medicine. Blackwells, Oxford, UK.


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