Lapis ISSN 2398-2969

Blood biochemistry: lactate dehydrogenase

Synonym(s): LD, LDH, Serum LDH, SLDH

Contributor(s): Michael Waters, Anna Meredith, Vetstream Ltd, John Chitty

Overview

  • May be divided into isoenzymes found principally in skeletal muscle, cardiac muscle, liver and red blood cells - not organ specific, but useful in assessment of tissue damage.
  • Longer half-life than creatine kinase.

Sampling

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Tests

Methodologies

  • Varies between laboratories (electrophoresis needed for LDH isoenymes).

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Test results most useful when interpreted in conjunction with other laboratory results and clinical findings.

LDH without isoenzymes is so non-specific that it is rarely interpretively useful.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Meredith A & Rayment L (2000) Liver disease in rabbits. Sem Avian Exotic Pet Med 9 (3), 146-152.
  • Benson K G & Paul-Murphy J (1999) Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract 2 (3), 539-552 PubMed.

Other sources of information

  • Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth-Heinemann, Elsevier, London, UK.
  • Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, Gloucester, UK. pp 124-137.
  • Saunders R A & Rees Davies R (2005) Notes on Rabbit Internal Medicine. Blackwells, Oxford, UK.


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