Lapis ISSN 2398-2969

Blood biochemistry: alanine aminotransferase (SGPT, ALT)

Synonym(s): ALT, Serum ALT, SALT, Glutamic-pyruvic transaminase, GPT, Serum GPT, SGPT

Contributor(s): Vetstream Ltd, Anna Meredith, Michael Waters, John Chitty

Overview

  • Released to serum after damage to, or proliferation of, hepatocytes.
  • Little tissue specificity in the rabbit. Heart muscle has similar ALT activity to liver.
  • However, do see significant elevations in ALT in conditions of hepatic damage and necrosis.

Sampling

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Tests

Methodologies

  • Varies between laboratories.

Availability

  • Widely available.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMedpublished during the last 12 months.
  • Meredith A & Rayment L (2000)Liver disease in rabbits. Sem Avian Exotic Pet Med9(3), 146-152.
  • Benson K G & Paul-Murphy J (1999)Clinical pathology of the domestic rabbit: acquisition and interpretation of samples. Vet Clin North Am Exotic Anim Pract2(3), 539-552PubMed.

Other sources of information

  • Varga M (2014) Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, London.
  • Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. pp 124-137. BSAVA, Gloucester UK.
  • Fudge A M (1999) Laboratory Medicine. Avian and Exotic Pets. W B Saunders Co. ISBN: 0721 676 790.


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