Lapis ISSN 2398-2969

Xylazine

Synonym(s): Rompun, Virbaxyl

Contributor(s): Molly Varga, Anna Meredith

Introduction

Name

  • Xylazine.

Class of drug

  • Alpha-2 adrenoreceptor agonist.

Description

Chemical name

  • N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine.

Molecular formula

  • C12H16N2S.

Molecular weight

  • 220.33.

Uses

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Indications

  • Sedation   Sedation  .
  • Chemical restraint.
  • Pre-anesthetic medication.
  • In conjunction with other drugs to produce surgical anesthesia.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with diagnostic tests

  • Causes transient increase in blood glucose levels.
  • Suppresses ADH secretion.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Difilippo S M, Norberg P J, Suson U D et al (2004) A comparison of xylazine and medetomidine in an anesthetic combination in New Zealand White rabbits. Contemp Top Lab Anim Sci 43 (1), 32-34 PubMed.

Other sources of information

Organisation(s)


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