Lapis ISSN 2398-2969

Thiopental

Synonym(s): Thiopentone

Contributor(s): Molly Varga, Anna Meredith

Introduction

Name

  • Thiopental.

No longer authorized for use in small animals in the UK.

Class of drug

  • Barbiturate anesthetic.

Description

Chemical name

  • (RS)-[5-ethyl-4,6-dioxo-5-(pentan-2-yl)-1,4,5,6-tetrahydropyrimidin-2-yl]sulfanide sodium.

Molecular formula

  • C11H17N2NaO2S.

Molecular weight

  • 264.32.

Physical properties

  • White/cream powder until reconstituted.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • A barbiturate anesthetic used for induction of anesthesia   Anesthesia: overview  .
  • Not generally recommended in rabbits due to low therapeutic index. Its use has largely been superseded by propofol   Propofol  .

Little analgesic effect.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

Other sources of information

Organisation(s)


ADDED