Lapis ISSN 2398-2969

Selamectin

Introduction

Name

  • Selamectin.

Class of drug

  • Avermectin parasiticide.

Description

Chemical name

  • (5Z,25S)-25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-5-demethoxy-25-de(2-methylpropyl)-22,23-dihydro-5-hydroxyiminoavermectin A1a.

Molecular formula

  • C43 H63 NO11.

Molecular weight

  • 770.0.

Physical properties

  • White powder.

Storage requirements

  • Store in the unopened foil package in a dry place.
  • Do not store above 30°C.
  • Highly flammable: keep away from heat, sparks, open flames or other sources of ignition.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications


Can be used in ivermectin-sensitive animals
  • Treatment and prevention of flea infestation caused byCtenocephalides spp  Ctenocephalides felis    Ctenocephalides canis  .
  • As part of strategy for treatment of flea allergy dermatitis.
  • Prevention of heartworm disease caused byDirofilaria immitiswith monthly administrations.
  • Treatment of ear mites (Psoroptes cuniculi  Psoroptes cuniculi  )   Ear mites  .
  • Treatment of sarcoptic mange caused bySarcoptes scabiei  Sarcoptes scabiei  .

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Bishop B Fet al(2000)Selamectin - a novel broad-spectrum endectocide for dogs and cats.Vet Parasitol91, 163-176.

Other sources of information

  • Hack R Jet alEfficiacy and safety of two different dose rates of Selamectin against naturally acquired infestations of Psoroptes cuniculi in rabbits.Proc BSAVA 2001, p552.

ADDED