Lapis ISSN 2398-2969

Nitrous oxide

Contributor(s): Anna Meredith

Introduction

Name

  • Nitrous oxide.

Class of drug

  • Inhalational anesthetic.

Uses

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Indications

  • In general nitrous oxide isnot recommended in rabbitsas it has a low MAC (minimum alveolar concentration of anesthetic) and only reduces required concentration of volatile agents by a small percentage (0.25-0.5%).
  • Used with oxygen to carry volatile anesthetics for the induction and maintenance of anesthesia. At induction it accelerates the uptake of volatile anesthetics and speeds induction.
  • During maintenance it reduces the inspired concentration of volatile anesthetic required, lowering the adverse effects of the latter (minimal effect in rabbits).
  • Recovery is more rapid due to less volatile anesthetic being administered over a given time (minimal effect in rabbits).

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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