ISSN 2398-2969      

Diazepam

Clapis
Contributor(s):

Jill Pearson


Introduction

Name

  • Diazepam.

Class of drug

  • Benzodiazepine.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Premedicant.
  • Anticonvulsant.
  • Anxiolytic.
  • Muscle relaxant, urethral muscle spasm.
  • Anesthesia.
  • May be used with ketamine   Ketamine  or fentanyl   Fentanyl  to offset the muscle hypertonicity associated with dissociative anesthesia.
  • Used in combination with acepromazine and/or opioids for pre-anesthetic medication in the critically ill patient.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

Cimetidine, erythromycin, and omeprazole
  • These drugs inhibit the metabolism of diazepam and may cause increased plasma concentrations.

Beta-1 antagonists

  • Duration of action of diazepam may be prolonged.
  • Hypotension may be enhanced if diazepam is used in conjunction with propranolol.

Antihistamines or opioid analgesics

  • Sedative effect may be enhanced.

Digoxin

  • The effects of digoxin may be increased.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Ghaffari M S, Moghaddassi A P & Bokaie S (2009) Effects of intramuscular acepromazine and diazepam on tear production in rabbits. Vet Rec 164 (5), 147-148 PubMed.

Other sources of information

  • Based on Small Animal Formulary. Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code