ISSN 2398-2969      

Cisapride

Clapis

Synonym(s): Prepulsid


Introduction

Name

  • Cisapride.

Class of drug

  • Prokinetic agent (promotes gastric emptying).

Description

Storage requirements

  • Store at room temperature.
  • Keep out of light and keep dry.

Uses

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Indications

  • Management of:
  • Gastrointestinal stasis.
  • Megacolon.

Administration

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Pharmacokinetics

Precautions

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Interactions

with other drugs

  • Opioid analgesics and antimuscarinics, eg atropine   Atropine  may antagonize cisapride's effects.
  • Fatal arrhythmia may be seen in conjunction with:
  • Erythromycin, clarythromycin, troleandomycin.
  • Itraconazole, ketoconazole, fluconazole and micoconazole.
  • Increases bioavailability of cyclosporine.
  • Increases absorption of aspirin, acetaminophen, diazepam, ethanol.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.
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