Lapis ISSN 2398-2969

Salmonellosis

Contributor(s): David Vella, Ron Rees Davies, Molly Varga, Lesa Thompson

Introduction

  • Salmonellosis is rare in the rabbit, and usually takes the form of acute or peracute septicemic disease rather than primarily diarrhea.
  • CauseSalmonella spp Salmonella spp.
  • Signs: diarrhea, depression, fever, abortion, death.
  • Diagnosis: bacteriology.
  • Treatment: fluid therapy, anti-endotoxic treatments, aggressive antibiosis.
  • Prognosis: poor when clinically affected.

Presenting signs

  • Depression.
  • Fever.
  • Abortions in pregnant does.
  • High mortality during an outbreak on an infected breeding unit.

Acute presentation

  • Sudden death is common, possibly with a short period of lethargy or some diarrhea.

Geographic incidence

  • Worldwide.

Sex predisposition

  • Females for abortion.

Public health considerations

  • Serious risk of zoonotic spread.

Potential for zoonotic infection.

  • Rabbit may have become infected as sentinel from another source, including potentially the human handlers.

Cost considerations

  • Treatment difficult.
  • Death of rabbits, often multiple deaths and abortions in an affected colony.

Pathogenesis

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Diagnosis

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Treatment

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Prevention

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Sequelae

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Solans L, Arnal J L, Sanz C et al (2019) Rabbit enteropathies on commercial farms in the Iberian Peninsula: Etiological agents identified in 2018–2019. Anim 9 (12), 1142 PubMed.
  • Xiao X, Pei L, Jiang L J et al (2018) In vivo pharmacokinetic/pharmacodynamic profiles of danofloxacin in rabbits infected with Salmonella typhimurium after oral administration. Front Pharmacol 9, 391 PubMed.
  • Bárcena-Varela S, Martínez-de-Tejada G, Martin L et al (2017) Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits. Experiment Molec Med 49 (6), e345-e345 PubMed.
  • Dawoud T M, Davis M L, Park S H et al (2017) The potential link between thermal resistance and virulence in Salmonella: a review. Front Vet Sc 4, 93 PubMed.

Other sources of information

  • Jenkins J R (1997) Gastrointestinal Diseases. In: Ferrets, Rabbits & Rodents: Clinical Medicine & Surgery. Eds: Hillyer E V & Quesenberry K E. Saunders, USA. pp 176-188.
  • Okerman L (1994) Diseases of Domestic Rabbits. 2nd edn. Blackwell, UK. pp 37-40, 102-103, 138.


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