Lapis ISSN 2398-2969

Kidney: polycystic disease

Contributor(s): Anna Meredith, Livia Benato

Introduction

  • Cause: congenital.
  • Signs: from asymptomatic to non-specific.
  • Diagnosis: biochemistry, ultrasonography, post mortem examination.
  • Treatment: none.
  • Prognosis: guarded.

Presenting signs

  • Most of the time it is asymptomatic.
  • Anorexia   Anorexia  .
  • Lethargy.
  • Enlarged kidney at palpation.

Breed predisposition

  • Reported in New Zealand White rabbits   New Zealand White  .
  • New Zealand rabbits are used as laboratory animals for the research and study of polycystic kidney disease in humans.

Pathogenesis

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Diagnosis

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Treatment

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Prevention

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Sequelae

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Further Reading

Publications

Refereed papers
  • Recent references fromPubMed.
  • Harcourt-Brown F (2007)Radiographic signs of renal disease in rabbits. Vet Rec160(23), 787-794PubMed.
  • Maurer K J, Marini R P, Fox J G et al(2004)Polycystic kidney syndrome in New Zealand white rabbits resembling human polycystic kidney disease. Kidney Int65(2), 482-489PubMed.

Other sources of information

  • Vennee K M & Mitchell M A (2009)Rabbits. In: Manual of Exotic Pet Practice.pp 375-405. 
  • Pare J A & Paul- Murphy J (2004)Disorders of the Reproductive and Urinary Systems.In: Ferrets, Rabbits and Rodents Clinical Medicine and Surgery. Eds: Quesenberry K  E & Carpenter J W. 2nd edn. Saunders. pp 183-193. 
  • Redrobe S (2000)Urogenital System and Disorders. In: BSAVA Manual of Rabbit Medicine and Surgery.Ed: Flecknell P. 47-55.
  • Lindsey J R & Fox R R (1994)Inherited diseases and Variations. In: The Biology of the Laboratory Rabbit. Eds: Manning P J, Ringler D H & Newcomers C E. 2nd edn. Academic Press. pp 293-313.


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