Lapis ISSN 2398-2969

Hypertension

Contributor(s): Aidan Raftery, Sarah Pellett

Introduction

  • Consistent increase in arterial blood pressure above the normal value for the species.
  • Cause: secondary, eg chronic renal failure.
  • Signs: PU/PD, behavioral changes.
  • Diagnosis: early screening and identification to prevent/delay progression of organ damage (kidney, heart, central nervous system, eyes).
  • Treatment: address underlying causes.
  • Prognosis: good if hypertension controlled and underlying disease managed.

Presenting signs

Acute presentation

  • May be diagnosed when severe organ damage occurred - cardiac failure and renal decompensation.

Age predisposition

  • Reported in the geriatric rabbit as a consequence of chronic renal disease or cardiac insufficiency.

Special risks

Pathogenesis

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Diagnosis

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Treatment

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Sequelae

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Further Reading

Publications

Refereed papers
  • Recent references fromPubMedandVetMedResource.
  • Chitty J (2015)Cardiovascular disease in rabbits. Comp Anim20(2), 74-78.
  • Lim K et al(2012)Comparison of blood pressure and sympathetic activity of rabbits in their home cage and laboratory environment. Exper Physiol97(12), 1263-1271PubMed.
  • Reusch B (2005)Investigation and management of cardiovascular disease in rabbits. In Pract27(8), 418-425VetMedResource.
  • Denton K M et al (2003)Adult rabbit offspring of mothers with secondary hypertension have increased blood pressure. J Hypertension41(3 Pt 2), 634-639PubMed.
  • Van Den Buuse M & Malpas S C (1997)24 hour recordings of blood pressure, heart rate and behavioural activity in rabbits by radiotelemetry: effects of feeding and hypertension.  Physiol Behav62(1), 83-89PubMed.
  • Bursztyn P G & King M H (1986)Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. J Hypertension4(6), 699-702PubMed.
  • Carroll J F, Dwyer T M & Grady A W (1986)Hypertension, cardiac hypertrophy and neurohormonal activity in a new animal model of obesity. Am Physiol Soc271(1 Pt 2), H373-378PubMed.

Other sources of information

  • Mancinelli E & Lord B (2014)Urogenital System and Reproductive Disease.In: BSAVA Manual of Rabbit Medicine.Eds: Meredith A & Lord B.  BSAVA, Gloucester. pp 191-204.
  • Orcutt C (2014)Cardiovascular Disease.In: BSAVA Manual of Rabbit Medicine.Eds: Meredith A & Lord B.  BSAVA, Gloucester. pp 205-213.
  • Varga M (2014)Textbook of Rabbit Medicine. 2nd edn. Butterworth Heinemann Elsevier, Edinburgh.
  • Fisher PG (2013)Renal Disorders.In: Clinical Veterinary Advisor. Birds and Exotics Pets. Eds: Mayer J & Donnelly T M. Elsevier, Missouri.
  • Raftery A (2013)Cardiovascular Disease.In: Clinical Veterinary Advisor. Birds and Exotics Pets.Eds: Mayer J & Donnelly T M.  Elsevier, Missouri.
  • Pollock C (2006)Therapeutics. In: BSAVA Manual of Rabbit Medicine and Surgery. 2nd edn. Eds: Meredith A & Flecknell P.  BSAVA, Gloucester.


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