Lapis ISSN 2398-2969

Orbit: deep gland – prolapse

Synonym(s): PDOG, Cherry eye

Contributor(s): William Lewis, Nathalie Wissink-Argilaga

Introduction

  • Cause:
    • Idiopathic
    • Possible trauma to orbital fascia.
    • Hormonal possibly: more common in intact male rabbits.
  • Signs: unilateral (rarely bilateral) prolapse of tissue behind the third eyelid.
  • Diagnosis: examination/biopsy of mass behind third eyelid.
  • Treatment: excision of deep portion of Harderian gland; castration?
  • Prognosis: excellent.
Print off the Owner Factsheet on Cherry eye to give to your clients.

Pathogenesis

Etiology

  • Uncertain.
  • Idiopathic.
  • Trauma to orbital fascia proposed.
  • Hormonal: testosterone.

Predisposing factors

Specific

  • Uncastrated males?
  • Growth of lacrimal gland stimulated by thyroxine and testosterone.

Pathophysiology

  • Possibly abnormal laxity of the connective tissue attaching Harderian gland to surrounding orbital structures.

Timecourse

  • Uncertain.
  • Rare and cases only presented when noticed by owners.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource
  • Bayraktaroğlu A G & Ergün E (2010) Histomorphology of the Harderian gland in the Angora rabbit. Anat Histol Embryol 39 (6), 494-502 PubMed.
  • Wagner F & Fehr M (2007) Common ophthalmic problems in pet rabbits. J Exot Pet Med 16 (3) 158-167 VetMedResource.
  • Volopich S, Gruber A, Hassan J et al (2005) Malignant B-cell lymphoma of the Harder’s gland in a rabbit. Vet Ophthalmol (4), 259-263 PubMed
  • Janssens G, Simoens P, Muylle S et al (1999) Bilateral prolapse of the deep gland of the third eyelid in a rabbit: diagnosis and treatment. Lab Anim Sci 49 (1), 105-109 PubMed.

Other sources of information

  • Knott T (2014) Ophthalmology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, UK. pp 244-245.
  • Fehr M (2013) Eye and Eyelid Surgery. In: BSAVA Manual of Rabbit Surgery, Dentistry and Imaging. Eds: Harcourt-Brown F & Chitty J. BSAVA, UK. pp 233-249
  • Harcourt-Brown F (2002) Ed. Ophthalmic Diseases. In: Textbook of Rabbit Medicine. Butterworth-Heinemann, UK. pp 292-306.


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