Lapis ISSN 2398-2969

Shope fibroma virus

Synonym(s): Rabbit (Shope firbroma virus

Contributor(s): Narelle Walter, Anna Meredith

Introduction

Classification

Taxonomy

Active Forms

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Clinical Effects

Epidemiology

Transmission

Pathological effects

  • Virus replicates at the site of entry and is transported to the draining lymph nodes where further virus replication causes viremia and subsequent development of widespread secondary skin lesions.
  • Mild infection results in multiple small, firm, pinkish spherical fibromas   Fibromatosis  . These are subcutaneous benign tumors.
  • In very young rabbits disease may become systemic and lethal.
  • Differential diagnosis of skin lesions are Myxoma virus   Myxoma virus  and early papilloma tumors   Papilloma virus  . Diagnosis is via biopsy.
  • Having been infected once, animals mount a good immune response and the condition is usually self-limiting in 6-8 weeks.

Other Host Effects

Control

Control via environment

  • Control of insect vectors.

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMed.
  • Keller Ret al(2007)Shope fibroma virus keratitis and spontaneous cataracts in a domestic rabbit.Vet Ophthal10(3), 190-195PubMed.
  • Krogstad A Pet al(2005)Viral disease of the rabbit.Vet Clin North Am Exotic Anim Pract8(1), 123-138.

Other sources of information

  • Quesenberry Ket al(2012)Ferrets, Rabbits and Rodents Clinical Medicine and Surgery.3rd edn. Elsevier.
  • Pragg E (2010)Skin diseases of Rabbits.Website:www.medirabbit.com.
  • Percy D Het al(2007)Pathology of Laboratory Rodents and Rabbits.3rd edn. Blackwell Publishing.

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