Lapis ISSN 2398-2969

Pox virus

Contributor(s): Narelle Walter, Susan Dawson

Introduction

Classification

Taxonomy

  • Family: Poxviridae.
  • Sub-family: Chordopoxvirinae.
  • Genus:Orthopoxvirus.

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Clinical Effects

Epidemiology

Transmission

  • High viral titers are found in the respiratory tract and transmission is likely to be airbourne.
  • Exact mode of transport is unclear at this stage.
  • Transmission is not via insects.

Pathological effects

  • Incubation is 2-4 days, with viremia occurring at day 2   Rabbitpox  .
  • Nasal discharge is often an initial presenting sign.
  • Generalized skin lesions appear at day 5; this may be seen as a rash and then isolated papules and nodules up to 1 cm.
  • Swollen face, fever and lymphadenopathy may also be seen.
  • Some strains have not presented with skin eruptions.
  • Death usually occurs in 5-20 days.

Control

Control via animal

  • Isolation and de-stocking of infected rabbit colonies is recommended.

Control via environment

  • To prevent indirect transmission by humans, good hygiene precautions essential; rabbitpox is not infective to humans.
  • Use of disinfectants, particularly hypochlorite (Domestos, Milton) on bedding, food dishes.

Vaccination

  • Vaccination with smallpox (vaccinia virus) gives protection against rabbitpox.

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMed.
  • Lei G (2005)Complete coding sequences of the rabbitpox virus genome.J Gen Virol 86 (pt 11), 2969-2977PubMed.
  • Cho C (1970) Viremia and virus measure of rabbit pox in CV 1 cells.Appl Microbiol19(5), 791-794PubMed.

Other sources of information


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