Lapis ISSN 2398-2969


Contributor(s): Vetstream Ltd, Anna Meredith




  • Family: Coronaviridae.
  • Genus:Coronavirus.
  • Species: Rabbitcoronavirus(RbCV)/Rabbit entericcoronavirus(RECV).


  • L:corona- crown: refers to the large club-shaped glycoprotein peplomers in the envelope of the virus.

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Clinical Effects



  • RECV has been observed in feces of clinically healthy adult rabbits.


  • Inapparent or persistent infections may occur   →   virus maintenance.
  • RECV - experimentally infected rabbits have been reported to shed virus for up to 29 days in feces.


  • RECV - fecal-oral, highly contagious.
  • RbCV - experimental infection of RbCV achieved via intramuscular inoculation, natural route not described.


Control via chemotherapies

  • Treat dehydration and supply electrolytes.

Control via environment

  • Attention to hygiene.
  • Avoid poor management conditions, eg overcrowding or stress.
  • Isolate infected individuals.


  • None available.


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Further Reading


Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Alexander L K, Keene B W, Yount B L et al (1999) ECG changes after rabbit coronavirus infection. J Electrocardiol 32 (1), 21-32 PubMed.
  • Alexander L K, Keene B W, Small J D et al (1993) Electrocardiographic changes following rabbit coronavirus-induced myocarditis and dilated cardiomyopathy. Adv Exp Med Biol 342, 365-370 PubMed.
  • Percy D H, Muckle C A, Hampson R J et al (1993) The enteritis complex in domestic rabbits: A field study. Can Vet J 34 (2), 95-102 PubMed.
  • Alexander L K, Small J D, Edwards S et al (1992) An experimental model for dilated cardiomyopathy after rabbit coronavirus infection. J Infect Dis 166 (5), 978-985 PubMed.
  • Edwards S, Small J D, Geratz J D et al (1992) An experimental model for myocarditis and congestive heart failure after rabbit coronavirus infection. J Infect Dis 165 (1), 134-140 PubMed.
  • Small J D & Woods R D (1987) Relatedness of rabbit coronavirus to other coronaviruses. Adv Exp Med Biol 218, 521-527 PubMed.
  • Descôteaux J P, Lussier G, Berthiaume L et al (1985) An enteric coronavirus of the rabbit: detection by immunoelectron microscopy and identification of structural polypeptides. Arch Virol 84 (3-4), 241-250 PubMed.
  • Eaton P (1984) Preliminary observations on enteritis associated with a coronavirus-like agent in rabbits. Lab Anim 18 (1), 71-74 PubMed.
  • Osterhaus A D, Teppema J S & van Steenis G (1982) Coronavirus-like particles in laboratory rabbits with different syndromes in the Netherlands. Lab Anim Sci 32 (6), 663-665 PubMed.
  • Lapierre J, Marsolais G, Pilon P et al (1980) Preliminary report on the observation of a coronavirus in the intestine of the laboratory rabbit. Can J Microbiol 26 (10), 1204-1208 PubMed.
  • Small J D, Aurelian L, Squire R A et al (1979) Rabbit cardiomyopathy associated with a virus antigenically related to human coronavirus strain 229E. Am J Pathol 95 (3), 709-729 PubMed.