Felis ISSN 2398-2950

Hematology: neutrophil

Contributor(s): Kathleen P Freeman, Karen L Gerber, Simon Tappin, Andy Torrance

Overview

  • Neutrophils phagocytose and digest foreign material in acute infectious or non-infectious inflammation.
  • The degree of [neutrophil] increase (neutrophilia) and presence or absence of left-shift provides a valuable diagnostic (in combination with other tests) and prognostic tool in many diseases.
  • Regenerative left-shift: neutrophilia with increased numbers of bands (mature neutrophils usually outnumber bands).
  • Degenerative left-shift: increased numbers of bands without increased numbers of mature neutrophils. Presence indicates that production and release are not meeting demand.
  • Marked left-shift (bands and metamyelocytes) Hematology: band neutrophil  →   acute to peracute, suppurative diseases. Any stage younger than the metamyelocyte is not capable of phagocytosis.
  • Neutrophils are short-lived (approximately 4 days).

Sampling

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Result Data

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Brown M R & Rogers K S (2001) Neutropenia in dogs and cats - a retrospective study of 261 cases. JAAHA 37, 131-139.
  • Lucroy M D& Madewell B (2001) Clinical outcome and diseases associated with extreme neutrophilic leukocytosis in cats - 104 cases (1991-1999). JAVMA 218, 736-739.

Other sources of information

  • Valenciano A C & Cowell R E (2013) Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat. 4th edn. St Louis: Mosby.
  • Day M & Kohn B (2012) BSAVA Manual of Canine and Feline Haematology and Transfusion Medicine. 2nd edn. BSAVA.
  • Latimer K S (2011) Duncan & Prasse'sVeterinary Laboratory Medicine: Clinical Pathology. 5th edn. Ames: Iowa University Press.
  • Stockham S L & Scott M A (2008) Fundamentals of Veterinary Clinical Pathology. 2nd edn. Blackwell Publishing.
  • Jain N C (1993) Essentials of Veterinary Hematology. Philadelphia: Lea & Febiger.


ADDED