Felis ISSN 2398-2950

Blood biochemistry: cholesterol

Contributor(s): Kathleen P Freeman

Overview

  • Major lipid in body and precursor of all steroid hormones and bile acids.
  • Obtained from diet and synthesized in liver.
  • Ancillary aid in diagnosis of several disorders but not diagnostic alone.

Sampling

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Tests

Methodologies

  • Enzymatic method most common.
  • Cholesterolesterase (hydrolyses cholesterol esters) and cholesteroloxidase are key enzymes.
  • If cholesterolesterase included, total cholesterol is measured.
  • If cholesterolesterase not included, non-esterified or 'free' cholesterol is measured.

Availability

  • Widely available.

Technique (intrinsic) limitations

  • Results only significant in conjunction with other laboratory results.

Result Data

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Watson T D G & Barrie J (1993) Metabolism and hyperlipidemia in the dog and cat. A review. JSAP 34, 479.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.


ADDED