ISSN 2398-2950      

Blood biochemistry: alanine aminotransferase (SGPT, ALT)

ffelis
Contributor(s):

Kathleen P Freeman

Synonym(s): ALT, Serum ALT, SALT, Glutamic-pyruvic transaminase, GPT, Serum GPT, SGPT


Overview

  • ALT may be elevated with liver or muscle damage/disease.
  • Highest concentration in hepatocytes, so considered most sensitive for hepatocellular damage.

Sampling

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Tests

Methodologies

  • Varies between laboratories.

Availability

  • Widely available.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lehmann A, Knutsson L & Bosaeus I (1990) Elevation of retinol levels and suppression of alanine aminotransferase activity in the liver of taurine-deficient kittens. J Nutr 120 (10), 1163-1170.

Other sources of information

  • Ettinger S J & Feldman E C (2000) Eds: Textbook of Veterinary Internal Medicine. 5th edn. W B Saunders & Co, USA.
  • Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.

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