Felis ISSN 2398-2950

Blood biochemistry: alanine aminotransferase (SGPT, ALT)

Synonym(s): ALT, Serum ALT, SALT, Glutamic-pyruvic transaminase, GPT, Serum GPT, SGPT

Contributor(s): Kathleen P Freeman

Overview

  • ALT may be elevated with liver or muscle damage/disease.
  • Highest concentration in hepatocytes, so considered most sensitive for hepatocellular damage.

Sampling

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Tests

Methodologies

  • Varies between laboratories.

Availability

  • Widely available.

Result Data

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Lehmann A, Knutsson L & Bosaeus I (1990) Elevation of retinol levels and suppression of alanine aminotransferase activity in the liver of taurine-deficient kittens. J Nutr 120(10), 1163-1170.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.


ADDED