Felis ISSN 2398-2950

Xylazine

Synonym(s): Rompun, Virbaxyl, Anased, Xyla-ject

Contributor(s): Stephen Greene

Introduction

Name

  • Xylazine.

Class of drug

  • Alpha-2 adrenoceptor agonist.

Description

Storage requirements

  • Store below 30°C.

Uses

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Indications

  • Sedation.
  • Chemical restraint.
  • Pre-anesthetic medication.
  • In conjunction with other drugs to produce surgical anesthesia.
  • Used to assess pituitary production of growth hormone.
  • To stimulate emesis.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • May get increased CNS depression if used with agents such as barbiturates, narcotics or anesthetics.
  • When combined with epinephrine may   →   cardiac arrhythmia.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Greene S A & Thurmon J C (1988)Xylazine - A review of its pharmacology and use in veterinary medicine.J Vet Pharmacol Therap11, 295-313.

Other sources of information

  • Based on Tennant, B (1999)Small Animal Formulary.3rd edn. Cheltenham: BSAVA.

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