Felis ISSN 2398-2950

Ticarcillin

Introduction

Name

  • Ticarcillin.

Class of drug

  • Carboxypenicillin antibiotic.

Description

Storage requirements

  • After reconstitution it is stable for 48-72 hours.

Uses

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Indications

  • Principally indicated for the treatment of serious (usually but not exclusively life threatening)Pseudomonas aeruginosainfections.
  • For pseudomonas septicemias ticarcillin should be given with an aminoglycoside (eg gentamicin   Gentamicin  ).
  • Activity against certain other Gram-negative bacilli includingProteusspp   Klebsiella pneumoniae  andBacteroides fragilis  Bacteroides fragilis  .

Administration

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Precautions

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Interactions

with other drugs

Aminoglycosides
  • Do not mix with ticarcillin because there is mutual inactivation.
  • Use with ticarcillin for pseudomonas septicemias as there is a synergistic effect. (Do not mix in the same syringe)

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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