Felis ISSN 2398-2950

Theophylline

Contributor(s): Elizabeth Rozanski

Introduction

Name

  • Theophylline.

Class of drug

  • Methylxanthine.

Uses

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Indications

  • Useful as a bronchodilator and in the management of pulmonary edema.

Administration

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Precautions

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Interactions

with other drugs

Phenobarbital
  • May decrease theophylline's effect   Phenobarbital  .

  • Cimetidine
  • Plasma theophylline levels may be increased   Cimetidine  .

  • Diltiazem
  • Plasma theophylline levels may be increased   Diltiazem  .

  • Erythromycin
  • Plasma theophylline levels may be increased   Erythromycin  .

  • Verapamil
  • Plasma theophylline levels may be increased   Verapamil  .

  • Pancuronium
  • Theophylline may decrease the effects   Pancuronium  .

  • Phenytoin
  • Theophylline may decrease the effects   Phenytoin  .

  • Beta-adrenergic blockers, eg propranolol
  • May antagonize each other   Propranolol  .

  • Anesthetics
  • There is an increased risk of dysrhythmias if theophylline is administered with halothane   Halothane  .
  • There is an increased incidence of seizures with ketamine   Ketamine  .
  • Hyperesthesia seen in cats.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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