Felis ISSN 2398-2950

Terbinafine

Contributor(s): Vetstream Ltd, Sue Paterson

Introduction

Class of drug

  • Allylamine antifungal agent.

Uses

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Indications

  • Treatment of dermatophytosis Skin: dermatophytosis in cats where systemic therapy is needed and licensed drugs are not suitable.
  • Malassezia dermatitis/otitis Malassezia dermatitis.
  • Subcutaneous and systemic fungal infections in cats.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Fewer potential drug interactions than ketoconazole Ketoconazole as does not inhibit cytochrome P450 system.

Rifampicin

  • Plasma concentrations of terbinafine decreased.

Cimetidine

  • Plasma concentrations of terbinafine increased.

Adverse Reactions

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Further Reading

Publications

Referred papers

  • Recent references from VetMed Resource and PubMed.
  • Moriello K A et al (2017) Diagnosis and treatment of dermatophytosis in dogs and cats: Clinical Consensus Guidelines of the World Association for Veterinary Dermatology. Vet Dermatol 28(3), 266-206 PubMed.

Other sources of information

  • Ramsey I (Editor in chief) (2014) BSAVA Small Animal Formulary. 8th edn. Gloucester: BSAVA.

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