Felis ISSN 2398-2950

Suxamethonium

Synonym(s): Succinycholine

Contributor(s): John Dodam

Introduction

Name

  • Suxamethonium.

Class of drug

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Few, if any, indications for use in the dog.
  • Used to facilitate endotracheal intubation in cats and primates.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

Do not use if organophosphorus flea treatment used in last month as this can prolong action of suxamethonium from days to weeks.

Drugs enhancing action of suxamethonium

Neostigmine and pyridostigmine

  • Should not be administered with suxamethonium as they inhibit pseudocholinesterases, thereby enhancing effect of suxamethonium.

Diazepam

  • May reduce the duration of action of suxamethonium.

Digoxin

  • Suxamethonium may cause a sudden outflux of potassium from muscle cells, which may initiate arrhythmias. This also happens in animals with denervation-type diseases.
    Anticholinesterase drugs aggravate blockade and prolong action.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED