Felis ISSN 2398-2950

Sodium valproate

Synonym(s): Epilim

Contributor(s): Kyle Braund

Introduction

Name

  • Sodium valproate.

Class of drug

  • Anticonvulsant.

Uses

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Indications

  • Convulsions   Epilepsy: idiopathic  .
  • May be useful in combination with other anticonvulsant drugs.

Administration

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Precautions

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Interactions

with other drugs

CNS active drugs
  • Valproic acid may enhance central nervous system (CNS) depression.

Salicylates

  • Salicylates may displace VPA from plasma protein sites, thus increasing VPA levels.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Frey H H (1989)Anticonvulsants drugs used in the treatment of epilepsy.Probe Vet Med1, 558-577.

Other sources of information

  • Based onSmall Animal Formulary.Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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