Felis ISSN 2398-2950

Sodium thiosulfate

Synonym(s): Sodium thiosulphate, Sodium hyposulfite

Contributor(s): Yolande Bishop

Introduction

Name

  • Sodium thiosulfate.

Class of drug

  • Antidote for cyanide (with sodium nitrite) poisoning.
  • Antifungal.

Description

Chemical name

  • Sodium thiosulfite.

Molecular formula

  • Na2O3S2.

Molecular weight

  • 158.11.

Physical properties

  • Powder.
  • Water soluble.
  • Insoluble in alcohol.

Uses

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Indications

  • Cyanide poisoning.
  • Fungal skin infections, eg:
    • Dermatophytosis.

Administration

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Further Reading

Publications

Refereed papers

  • Beasley D M, Glass W I (1998)Cyanide poisoning - pathophysiology and treatment recommendations.Occup Med (Lond)48(7) 427-231.
  • Bhattacharya R (1995)Therapeutic efficacy of sodium nitrite and 4-dimethylaminophenol or hydroxylamine co-administration against cyanide poisoning in rats.Hum Exp Toxicol14(1) 29-33.
  • Koller W, Rotter M L and Gottardi W (1995)Do 'chlorine covers' exert a sustained bactericidal effect on the bacterial hand flora?J Hosp Infect31(3) 169-176.

Other sources of information

  • Tennant B (1999)Small Animal Formulary.3rd edn. British Small Animal Veterinary Association. ISBN 0 905214 52 8.
  • The Veterinary Formulary.

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