Felis ISSN 2398-2950

Sodium bicarbonate

Synonym(s): Bicarbonate of soda, baking soda

Contributor(s): Melissa Wallace

Introduction

Name

  • Sodium bicarbonate.

Class of drug

  • Electrolyte.
  • Alkalinizing agent.

Description

Molecular formula

  • NaHCO3

Physical properties

  • Soluble in water.

Storage requirements

  • Tablets and powder.
    • Store in air-tight containers at room temperature.
  • Injection.
    • Store at room temperature, avoid freezing.

Uses

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Indications

  • Treatment of metabolic acidosis .
  • To alkalinize urine.
  • Adjunctive therapy in the treatment of hypercalcemic or hyperkalemic crises.

Administration

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Precautions

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Interactions

with other drugs

Quinidine
  • Alkalinization of urine by sodium bicarbonate decreases the excretion of quinidine.

Sympathomimetic drugs

  • Alkalinization of urine by sodium bicarbonate decreases the excretion.

Aspirin

  • Increases the excretion of aspirin.

Phenobarbital

  • Increases the excretion of phenobarbital.

Tetracyclines (especially doxycycline)

  • Increases the excretion of tetracyclines.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
  • Based on Plumb DC (2002)Veterinary Drug Handbook. 4th edition. Iowa State Press, Ames, Iowa.

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