Felis ISSN 2398-2950

Ranitidine

Synonym(s): Zantac

Introduction

Name

  • Ranitidine.

Class of drug

  • Histamine (H2) receptor antagonist.

Uses

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Indications

  • Used to treat gastric and duodenal ulcers (including NSAID induced ulceration   Analgesia: NSAID  ).
  • Used prophylactically to prevent stress ulcers.
  • Adjunct therapy for reversing metabolic alkalosis.
  • Treatment of Helicobacter gastritis   Gastritis: helicobacter  in combination with antibiotics.
    4-10 times more potent than cimetidine   Cimetidine  and has minimal effects on hepatic enzymes.
  • Immunomodulation.

Administration

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Precautions

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Interactions

with other drugs

Antacids, digoxin, ketoconazole or metoclopropamide
  • Ranitidine may reduce their absorption or effect.

Sucralfate

  • Reduces the absorption of ranitidine.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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