Felis ISSN 2398-2950

Pregabalin

Contributor(s): Laurent Garosi, Mark Lowrie

Introduction

Name

  • Pregabalin.

Class of drug

  • GABA analogue.

Description

Chemical name

  • (S)-3-aminomethyl-5-methylhexanoic acid.

Uses

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Indications

  • Mono- or adjunctive anti-epileptic drug.
  • Treatment of neuropathic pain.

Administration

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Pharmocokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from VetMed Resource and PubMed.
  • Moore SA (2016) Managing neuropathic pain in dogs. Front Vet Sci 3, 12 PubMed.
  • Muñana K R (2013) Management of refractory epilepsy. Top Companion Anim Med 28, 67-71 PubMed.
  • Plessas I N, Rusbridge C, Driver C J et al (2012) Long-term outcome of Cavalier King Charles spaniel dogs with clinical signs associated with Chiari-like malformation and syringomyelia. Vet Rec 171, 501 PubMed.
  • Dewey C W, Cerda-Gonzalez S, Levine J M et al (2009) Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy. J Am Vet Med Assoc 235, 1442-1449 PubMed.
  • Salazar V, Dewey CW, Schwark W et al (2009) Pharmacokinetics of single-dose oral pregabalin administration in normal dogsVet Anaesthesia and analgesia 36, 574-580 PubMed.

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