Felis ISSN 2398-2950

Pimobendan

Contributor(s): Yolande Bishop, Sonja Fonfara

Introduction

Name

  • USAN.
  • rINN.

Class of drug

  • Inodilator.
  • Vasodilator.

Description

Chemical name

  • 4,5-Dihydro-6-[2-(p-methyoxyphenyl)-5-benzimidazolyl]-5-methyl-3(2H-pyridazinone).

Molecular formula

  • C19H18N4O2.

Molecular weight

  • 334.4.

Storage requirements

  • Do not store above 25° C.
  • Store in a dry place.

Uses

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Indications

  • No evidence present so far, abstracts presented for use in cats:
    • Off license use in cats with endstage myocardial disease with systolic and diastolic dysfunction and refractory congestive heart failure   Heart: congestive heart failure  .

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Verapamil   →   reduced action of pimobendan.
  • Propranolol   →   reduced action of pimobendan.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • McGregor (2010)ACVIM abstract 2010:Use of Pimobendan in 161 cats.
  • Gordon S (2010)ACVIM abstract 2010: Use of Pimobendan in 28 cats with cardiac disease.
  • The Veterinary Formulary.5th edn (2001) Bishop, Y (Ed.) British Veterinary Association and Pharmaceutical Press.

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