Felis ISSN 2398-2950

Phenylpropanolamine - diphenylpyraline

Synonym(s): PPA

Contributor(s): Melissa Wallace

Introduction

Name

  • Phenylpropanolamine.

Class of drug

  • Sympathomimetic amine.

Uses

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Indications

  • Management of urinary incontinence   Urinary incontinence  by increasing urethral outflow resistance.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Monamine oxidase (MAO) inhibitors - do not give PPA within 2 weeks of MAO inhibitors.
  • Avoid with other sympathomimetics (eg ephedrine, epinephrine   Epinephrine  ).
  • Avoid use with concurrent NSAIDs as may increase risk of hypertension.
  • Can cause cardiac arrhythmias if given with halogenated hydrocarbon anesthetic agents.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D C (2002)Veterinary Drug Handbook. 4th edition. Iowa State University Press, Ames, Iowa.
  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 9052 1452 8.

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