Felis ISSN 2398-2950

Phenylephrine

Contributor(s): Sheryl Krohne

Introduction

Name

  • Phenylephrine.

Class of drug

  • Alpha-1 selective adrenergic agonist.

Uses

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Indications

  • Used in conjunction with fluid therapy, to treat hypotension secondary to drug overdose.
  • Used to slow conjunctival hemorrhage during surgery. It is used before some types of intraocular surgery to blanch conjunctival vessels.
  • When applied topically to the eye phenylephrine causes vasoconstriction and pupil dilation. It is indicated for some diagnostic eye examinations, such as diagnosing Horner's syndrome.

Administration

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Precautions

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Interactions

with other drugs

Volatile anesthetics
  • Risk of arrhythmias.

Oxytocic agents

  • Pressor effects may be enhanced leading to severe hypertension.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based on Tennant B (1999)Small Animal Formulary.3rd edn. Cheltenham: BSAVA.
  • Regnier A & Ward D (1999)Clinical Pharmacology and Therapeutics.In:Veterinary Ophthalmology3rd edn. Ed K Gelatt. Baltimore: Lippincott, Williams and Wilkins.
  • Plumb D (1999)Veterinary Drug Handbook.3rd edn. Ames: Iowa State University Press.

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