Felis ISSN 2398-2950

Phenoxyethanol

Contributor(s): Yolande Bishop

Introduction

Name

  • Phenoxyethanol.

Class of drug

  • Antiseptic agent.

Description

Chemical name

  • 1-hydroxy-2-phenoxyethane.
  • Ethylene glycol monophenyl ether.
  • Beta-hydroxyethyl phenyl ether.

Molecular formula

  • C8H10O2.
  • C6H5OCH2CH2OH.

Molecular weight

  • 138.17.

Physical properties

  • Oily liquid.
  • Slightly aromatic odor.
  • Partially soluble in water.
  • Very soluble in alcohol, ether and NaOH solutions.

Uses

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Indications

  • Bacterial skin infections.
  • Cleansing of contaminated wounds.

Administration

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Roper C S et al (1997)Percutaneous penetration of 2-phenoxyethanol through rat and human skin.Food Chem Toxicol35(10-11) 1009-1016.
  • Mitchell P et al (1993)Phenoxyethanol is effective topical therapy of gram-negative cellulitis in neutropenic patients.J Hosp Infect25(1) 53-56.
  • Scortichini B H et al (1987)Teratologic evaluation of 2-phenoxyethanol in New Zealand White rabbits following dermal exposure.Fundam Appl Toxicol8(2) 272-279.

Other sources of information

  • Tennant B (1999)Small Animal Formulary.3rd edn. British Small Animal Veterinary Association. ISBN 0 905214 52 8.

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