Felis ISSN 2398-2950

Pentobarbital

Synonym(s): Pentobarbitone

Contributor(s): Kyle Braund

Introduction

Name

  • Pentobarbital.

Class of drug

  • Short-acting barbiturate.
  • Schedule II Controlled Substance

Uses

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Indications

  • A short-acting barbiturate which may be used as an IV anesthetic, as an anticonvulsant to treat acute seizures or for euthanasia.

Administration

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Precautions

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Interactions

with other drugs

Drugs which may increase the effect of pentobarbital
  • Chloramphenicol   Chloramphenicol  .
  • Other central nervous system (CNS) depressants (antihistamines, narcotics, phenothiazines).
  • Valproic acid   Sodium valproate  .

Drugs acted on by pentobarbital (enhanced metabolism/decreased effect)

Barbiturates

  • May enhance the effects of other antiepileptics.

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
  • Plumb DC (1999)Veterinary Drug Handbook.3rd edn. Iowa State University Press, Ames. pp 265-266, 496-499

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