Felis ISSN 2398-2950

Octreotide

Synonym(s): Sandostatin*

Introduction

Name

  • Octreotide.

Class of drug

  • A long-acting analogue of the hypothalamic hormone somatostatin.

Description

Chemical name

  • D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2->7)-disulfide.

Molecular formula

  • C49H66N10O10S2.

Uses

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Indications

  • May be useful in the management of gastric, enteric and pancreatic endocrine tumors (eg insulinoma   Insulinoma  , gastrinoma ) and acromegaly   Acromegaly  although variable responses have been reported in veterinary medicine.
  • Tumors not expressing somatostatin receptors will not respond.

Administration

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Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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