ISSN 2398-2950      

Naloxone

ffelis

Synonym(s): Naloxone HCl


Introduction

Name

  • Naloxone.

Class of drug

  • Opioid antagonist.

Uses

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Indications

  • Indicated for treatment of gross overdosage of all narcotic including agonist/antagonists (eg butorphanol, nalbuphine).
  • Has been used in the management shock (high doses).
  • To identify persistent opioid activity ( a small IV dose will give transient increase in consciousness when persistent opioid activity contributes to prolonged anesthetic recovery).

Administration

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Precautions

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Interactions

with other drugs

Narcotics

  • The narcotic effects may persist longer than that of naloxone, therefore monitor animals being treated for overdose carefully, until the narcotic effects remain negated.
  • Naloxone will also reverse the analgesic effects of narcotics.

Publications

Refereed papers

Other sources of information

  • Ramsey I (2017) BSAVA Small Animal Formulary. 9th edn. 
  • Based on Small Animal Formulary. Tennant B (1999) 3rd edn. BSAVA, UK.
  • Plumb D C (1999) Veterinary Drug Handbook. 3rd edn. Iowa State University Press, USA. pp 445-446.
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