Felis ISSN 2398-2950

Metoclopramide

Introduction

Name

  • Metoclopramide.

Class of drug

  • Antiemetic.
  • Upper gastrointestinal tract stimulant.

Uses

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Indications

  • Acts as an antiemetic and an upper gastrointestinal (GI) stimulant.
  • Management of gastrointestinal reflux.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Antimuscarinic drugs (eg atropine) and narcotic analgesics
  • The activity of metoclopropamide may be inhibited.
    Insulin
  • The absorption of food may be accelerated thereby altering insulin requirements and/or timing of its effects.
    Phenothiazines
  • May potentiate the extrapyramidal effects of metoclopramide.
    Narcotics, sedatives or tranquilizers
  • The central nervous system (CNS) effects of metoclopramide may be enhanced.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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