Felis ISSN 2398-2950

Methyltestosterone

Introduction

Name

  • Methyltestosterone.

Class of drug

  • Androgenic steroid hormone.

Uses

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Indications

  • Pseudopregnancy   Pseudopregnancy  in the bitch.
  • Treatment of anemia in chronic renal failure   Kidney: chronic kidney disease  (controversial).
  • Treatment of testosterone-responsive incontinence in neutered male dogs.
  • Treatment of deficient sex drive in male animals. .
  • Reversion of feminization in male dogs following removal of estrogenic testicular tumors.
  • Treatment of estrogen dependent mammary tumors   Mammary gland: neoplasia  , estrogen suppression in the bitch.
  • Possible use in certain skin conditions, eg feline endocrine alopecia   Psychogenic alopecia  , hypogonadism, senile alopecia in male dogs.
  • Its use in the treatment for debility or senile decline is controversial.
  • Note: Sesoral is only indicated for the treatment of pseudopregnancy.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Insulin
  • The insulin requirements in diabetic patients may be altered.
    Corticosteroids
  • May potentiate the development of edema.
    Anticoagulants and clotting factors
  • Androgens may suppress the activity of clotting factors II, V, VII, and X and increase bleeding in patients on anticoagulant therapy.

with diagnostic tests

  • May cause increased serum creatinine levels and creatinine excretion.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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