Felis ISSN 2398-2950

Lidocaine

Synonym(s): Lignocaine

Contributor(s): Kyle Braund

Introduction

Name

  • Lidocaine.

Class of drug

  • Amide-linked local anesthetic.
  • Class 1B antidysrhythmic.

Uses

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Indications

  • Drug of choice for treating acute ventricular dysrhythmias   Heart: dysrhythmia  .
  • Used predominantly as a local anesthetic.

Administration

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Precautions

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Interactions

with other drugs

Cimetidine
  • May increase serum lidocaine levels or its effects if administered concurrently.

Propranolol

  • May increase serum lidocaine levels or its effects if administered concurrently.

Procainamide

  • May cause additive CNS effects.

Other anti-dysrhythmics

  • May cause increased myocardial depression.

Acetazolamide, loop diuretics and thiazides

  • The effect of lidocaine may be antagonized by hypokalemia with the above drugs.

Suxamethonium

  • Large doses of lidocaine may prolong suxamethonium-induced apnea.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Cassutto B H & Gfeller R W (2003)Use of intravenous lidocaine to prevent reperfusion injury and subsequent multiple organ dysfunction syndrome.J Vet Emerg Crit Care.13(3), 137.DOI
  • Jones RS (2001)Epidural analgesia in the dog and cat.Vet J.161(2), 123-131.
  • Lemke KA & Dawson SD (2000)Local and regional anesthesia.Vet Clin North Am Small Anim Pract.30(4), 839-857.

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
  • Plumb DC (1999)Veterinary Drug Handbook. 3rd edn. Iowa State University Press, Ames. pp 379-381.

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