Felis ISSN 2398-2950

Lactitol

Introduction

Name

  • Lactitol.

Class of drug

  • Laxative.

Uses

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Indications

Laxative
  • Due to its metabolism by colonic bacteria resulting in the formation of low molecular weight organic acids (lactic, formic, acetic acids) and CO2. These acids increase osmotic pressure drawing water into the bowel causing a laxative effect and acidify colonic contents.

  • Hepatic encephalopathy
  • The acidification of the colonic contents causes ammonia to be trapped as ammonium ions, which are then expelled with the feces, thus reducing blood ammonia levels.
  • Better tolerated by animals than lactulose due to different taste.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Oral antibiotics
  • Synergism may occur.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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