ISSN 2398-2950      

Ketamine

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Introduction

Name

  • Ketamine.

Class of drug

Description

Chemical name

  • (+/-)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone.

Molecular formula

  • C13H16ClNO

Physical properties

  • Clear solution.

Storage requirements

Uses

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Indications

  • A dissociative anesthetic/analgesic used to provide restraint or dissociative anesthesia.
  • Dissociative anesthesia is associated with mild stimulation of cardiac output and blood pressure, modest respiratory depression and preservation of cranial nerve reflexes.
    Eyes remain open during anesthesia. Thus a bland ophthalmic lubricant should be used.Ketamine alone does not provide sufficient analgesia for ovariohysterectomy Ovariohysterectomy
  • Provision of intra-operative and post-operative analgesia when administered intravenously by continuous rate infusion (CRI). May be particularly useful to provide analgesia in animals with upregulated pain states.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Jones R  S (2001) Epidural analgesia in the dog and cat. Vet J (2), 123-131.
  • Loeven K O (2000) Reservations about detomidine-ketamine combination. J Am Vet Med Assoc 217(4), 467-468.
  • Cruz M L, Luna S P, de Castro G B, Massone F & Rosa A L (2000) A preliminary trial comparison of several anesthetic techniques in cats. Can Vet J 41(6), 481-485.

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 9052 1452 8.
  • Plumb D C (1999) Veterinary Drug Handbook. 3rd edn. Iowa State University Press, Ames. pp 362-365.
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