ISSN 2398-2950      

Imepitoin

ffelis

Synonym(s): Pexion®


Introduction

Name

  • Imepitoin.

Class of drug

  • Anti-epileptic.

Description

Chemical name

  • Imepitoin.

Molecular formula

  • C13H14ClN3O2

Molecular weight

  • 279.7222

Uses

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Indications

  • Imepitoin is widely used for the reduction of the frequency of generalized seizures due to idiopathic epilepsy Epilepsy: idiopathic in dogs for use after careful evaluation of alternative treatment options Seizure: management.
  • Its efficacy in cats remains limited. Only one study has reported its use with the following findings:
    • Population - 8 epileptic cats with ≥2 seizures within the preceding 2 weeks of study enrolment, ≥9 months of age.
    • Treatment period ≥8 weeks.
    • Outcome measure - cats with ≥8 weeks seizure freedom considered success, cats with ≥50% reduction in seizure frequency considered parital success.
    • 4/8 had treatment success, 1/8 partial success, 2/8 continued to seizure without success and 1/8 lost to follow up.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Engel O, van Klopmann T, Maiolini A, Freundt-Revilla J & Tipold A (2017) Imepitoin is well tolerated in healthy and epileptic cats. BMC Vet Res 13(1) doi: 10.1186/s12917-017-1087-3.

Other sources of information

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