Felis ISSN 2398-2950

Heparin

Contributor(s): Mark Rishniw

Introduction

Name

  • Heparin.

Class of drug

  • Anticoagulant.

Description

Physical properties

  • Heterogeneous group of glycosaminoglycans.

Storage requirements

  • Room temperature.

Uses

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Indications

  • Given to promote anticoagulation.
  • Primary uses in small animal medicine include the treatment of disseminated intravascular coagulation (DIC) and thromboembolic disease , and the maintenance of IV catheter patency.
    Use in DIC is controversial and information on efficacy is lacking.
  • Feline aortic thromboembolism - efficacy questionable.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

ACTH
  • May antagonize the actions of ACTH.

Corticosteroids

  • May antagonize the actions of corticosteroids.

Insulin

  • May antagonize the actions of insulin.

Diazepam

  • May increase plasma levels of diazepam.

Antihistamines, digoxin and tetracyclines

  • The actions of heparin may be partially counteracted.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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