Felis ISSN 2398-2950

Flucloxacillin

Introduction

Class of drug

  • Beta-lactamase resistant narrow spectrum beta-lactam antibiotic.

Uses

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Indications

  • Treatment of infections with beta-lactamase-producingStaphylococcusspp   Staphylococcus spp  .

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Bacteriostatic antibiotics
  • Avoid concomitant use of bacteriostatic antibiotics eg chloramphenicol   Chloramphenicol  , erythromycin   Erythromycin  , tetracycline   Tetracycline  .
    Probencid
  • Blocks renal tubular excretion of penicillins   →   higher, more prolonged plasma concentrations.
    Aminoglycosides
  • May inactivate penicillins if mixed in same syringe.

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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