Felis ISSN 2398-2950

Filgrastim

Synonym(s): Neopogen

Introduction

Name

  • Filgrastim (G-CSF).

Class of drug

  • Recombinant human granulocyte-colony stimulating factor.
  • Glycoprotein produced by bone marrow, stromal cells, monocytes/macrophages, fibroblasts and endothelial cells.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Indicated in the management of neutropenia. Neutrophil counts rise within 24 hours. Following discontinuation of therapy, neutrophil counts drop to normal after 5 days.
  • Most likely to be used in febrile patients with neutrophil counts of less than 1x10*9/l.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED