Felis ISSN 2398-2950

Dobutamine

Contributor(s): Mark Rishniw

Introduction

Name

  • Dobutamine.

Class of drug

  • Principally a beta 1-adrenoceptor agonistwith lesser degrees of alpha1 and beta2 agonist effects.

Description

Chemical name

  • 1,2-benzenediol,4-[2-[3-(4-hydroxyphenyl)-1-methylpropyl] amino]ethyl]-,HCl

Molecular weight

  • 301

Physical properties

  • crystalline powder

Storage requirements

  • Reconstituted IV solution is stable for 24 hours although a slight color change may occur during this period.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

Beta-blockers (eg propranolol)
  • Dobutamine may be ineffective if beta-blockers   Propranolol  have recently been given.

  • Nitroprusside
  • A synergistic effect on the improvement of cardiac output has been recorded with nitroprusside   Nitroprusside  .

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED