Felis ISSN 2398-2950

Digoxin

Synonym(s): Lanoxin, digitalis

Contributor(s): Mark Rishniw

Introduction

Name

  • Digoxin.

Class of drug

  • Cardiac glycoside.

Description

Molecular formula

  • C41H64O14

Molecular weight

  • 781

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Drugs reducing digoxin absorption from gastrointestinal (GI) tract

Drugs affecting digoxin (increase serum level, decrease elimination rate or enhance the toxic effects)

Spironolactone

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Atkins C E, Snyder P S, Keene B W, Rush J E & Eicker S (1990)Efficacy of digoxin for treatment of cats with dilated cardiomyopathy.JAVMA196(9), 1463-1469.
  • Atkins C E, Snyder P S, Keene B W & Rush J E (1989)Effects of compensated heart failure on digoxin pharmacokinetics in cats.JAVMA195(7), 945-950.
  • Atkins C E, Snyder P & Keene B W (1988)Effect of aspirin, furosemide, and commercial low-salt diet on digoxin pharmacokinetic properties in clinically normal cats.JAVMA193(10), 1264-1268.
  • Erichsen D F, Harris S G & Upson D W (1980)Therapeutic and toxic plasma concentrations of digoxin in the cat.Am J Vet Res41(12), 2049-2058.

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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