ISSN 2398-2950      

Diazepam

ffelis
Contributor(s):

Kyle Braund


Introduction

Name

  • Diazepam.

Class of drug

  • Benzodiazepine.
  • Schedule IV Controlled Substance.

Uses

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Indications

  • Premedicant.
  • Anticonvulsant.
  • Anxiolytic.
  • Muscle relaxant, eg Scotty cramp , urethral muscle spasm, tetanus   Tetanus  .
  • Appetite stimulant.
  • Spraying.
  • Anesthesia (small mammal/bird).
  • May be used with ketamine to offset the muscle hypertonicity associated with dissociative anesthesia.
  • Used in combination with acepromazine   Acepromazine maleate  and/or opioids for preanesthetic medication in the critically ill patient.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

Cimetidine, erythromycin, and omeprazole

Beta1 antagonists

  • Duration of action of diazepam may be prolonged.
  • Hypotension may be enhanced if diazepam is used in conjunction with propranolol.

Antihistamines or opioid analgesics

  • Sedative effect may be enhanced.

Digoxin

  • The effects of digoxin   Digoxin  may be increased.

Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Podell M (1998)Antiepileptic drug therapy. Clin Tech Small Anim Pract 13 (3), 185-192.
  • Quesnel A D, Parent J M & McDonell W (1997) Clinical management and outcome of cats with seizure disorders: 30 cases (1991-1993). JAVMA 210 (1), 72-77

Other sources of information

  • Based on Small Animal Formulary. Tennant B (1999) 3rd edn. BSAVA, UK.
  • Plumb D C (1999) Veterinary Drug Handbook. 3rd edn. Iowa State University Press, USA pp 184-187.
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