Felis ISSN 2398-2950

Cisplatin

Contributor(s): William Brewer Jr, Laura Garrett

Introduction

Name

  • Cisplatin.

Class of drug

Uses

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Indications

  • Cell cycle non-specific antineoplastic agent against various sarcomas and carcinomas.
  • Used most commonly in the management of osteosarcoma.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Aminoglycosides
  • Increase risk of nephrotoxicity, ototoxicity.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Fischer D S, Knobf M Tet al(2003)The Cancer Chemotherapy Handbook. 6th edn. Philadelphia, PA, Mosby. pp 86-88.
  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
  • Theon A (1997)Intratumoral Chemotherapy in Small Animals.In:Proceedings of the 15th Annual Veterinary Medical Forum American College of Veterinary Internal Medicine.pp 180-181.
  • Fraizier D L & Hahn K A (1995)Commonly Used Drugs.In: Hahn K A & Richardson R C (eds)Cancer Chemotherapy A Veterinary Handbook. Philadelphia, PA. Williams & Wilkins. pp 92-93.

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